Related Experiment Video
Updated: Mar 17, 2026
Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
Malignant pleural mesothelioma with lacrimal gland metastasis
Hanida Hanafi1, Rob M Verdijk2, Dion Paridaens1
1Department of Oculoplastic and Orbital Surgery, The Rotterdam Eye Hospital, Rotterdam, the Netherlands.
Purpose:
To describe a rare clinical case of biopsy-proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy.
Methods:
Interventional case report.
Results:
A 55-year-old woman with an untreated malignant biopsy-proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy.
Conclusions:
Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.
