Compact pairwise models for epidemics with multiple infectious stages on degree heterogeneous and clustered networks
N Sherborne1, K B Blyuss1, I Z Kiss1
1Department of Mathematics, University of Sussex, Brighton BN1 9QH, UK.
Abstract:
This paper presents a compact pairwise model describing the spread of multi-stage epidemics on networks. The multi-stage model corresponds to a gamma-distributed infectious period which interpolates between the classical Markovian models with exponentially distributed infectious period and epidemics with a constant infectious period. We show how the compact approach leads to a system of equations whose size is independent of the range of node degrees, thus significantly reducing the complexity of the model. Network clustering is incorporated into the model to provide a more accurate representation of realistic contact networks, and the accuracy of proposed closures is analysed for different levels of clustering and number of infection stages. Our results support recent findings that standard closure techniques are likely to perform better when the infectious period is constant.
More Related Videos
08:03Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
10:11Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
Published on: September 27, 2014
Related Concept Videos
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Steps in Outbreak Investigation
Modeling with Differential Equations
Pharmacodynamic Models: Additive and Proportional Drug Effect Model
Statistical Methods for Analyzing Epidemiological Data
Pharmacodynamic Models: Link Model and Systems Pharmacodynamic Model
