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Towards a multi-dimensional approach to COPD.

Alessandro Zanforlin1, Claudio Sorino, Giuseppe F Sferrazza Papa

  • 1Multidisciplinary Medical Department, San Luca Hospital, Trecenta, Rovigo, Italy - alessandro.zanforlin@gmail.com.

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|July 19, 2016
PubMed
Summary
This summary is machine-generated.

Chronic obstructive pulmonary disease (COPD) may affect individuals with normal spirometry. Chest imaging and functional tests could offer a more comprehensive assessment for early COPD detection.

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Area of Science:

  • Pulmonary Medicine
  • Radiology
  • Respiratory Physiology

Background:

  • Chronic obstructive pulmonary disease (COPD) is a major global cause of death.
  • Current guidelines do not classify individuals with symptoms and smoke exposure but normal spirometry (FEV1/FVC ratio) as affected.
  • The GeneCOPD study indicates potential radiological abnormalities in this population.

Purpose of the Study:

  • To explore the future role of advanced imaging and functional tests in assessing COPD.
  • To propose a multidimensional approach for evaluating individuals with potential early-stage COPD.

Main Methods:

  • Review of current COPD classification and limitations.
  • Discussion of the potential utility of chest imaging (e.g., ultrasound of respiratory muscles).
  • Integration of functional tests like body plethysmography and diffusing capacity for carbon monoxide (DLCO).

Main Results:

  • Individuals with smoke exposure and symptoms but normal spirometry may exhibit significant radiological findings.
  • A multidimensional assessment could provide a more nuanced understanding of respiratory disease.

Conclusions:

  • Chest imaging and complementary functional tests may be crucial for a comprehensive COPD assessment.
  • This approach could redefine the evaluation of individuals at risk for or in the early stages of COPD.