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Updated: Mar 17, 2026

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Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders
Published on: February 3, 2021
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Summary
Most chest pain in athletes is not heart-related and resolves on its own. However, when cardiac issues are suspected, prompt diagnosis is crucial for appropriate treatment and athlete safety.
Area of Science:
- Sports Medicine
- Cardiology
- Diagnostic Imaging
Background:
- Chest pain in athletes is common, often benign and noncardiac.
- Cardiac causes of chest pain in athletes require accurate and timely diagnosis.
- Identifying underlying cardiac conditions is vital for preventing serious adverse events.
Purpose of the Study:
- To outline diagnostic strategies for chest pain in athletes.
- To differentiate between cardiac and noncardiac causes of chest pain.
- To emphasize the importance of cardiac evaluation when indicated.
Main Methods:
- Clinical history and physical examination are initial steps.
- Electrocardiography (ECG) and echocardiography are key diagnostic tools.
- Exercise stress testing, including thallium scans, aids in diagnosis.
Main Results:
- Noncardiac chest pain is frequent and usually self-limiting.
- Specific ECG findings (hypertrophy, Q waves) and murmurs warrant further cardiac investigation.
- Diagnostic tests can help identify hypertrophic cardiomyopathy and other cardiac conditions.
Conclusions:
- Accurate diagnosis of cardiac chest pain in athletes is imperative.
- A stepwise diagnostic approach is effective in identifying the source of chest pain.
- Further investigations, including medication trials, may be needed for inconclusive cases.
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