Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Randomized, Nivolumab-controlled, Phase 2 and Biomarker Study of Lomvastomig and Tobemstomig in Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same author

Erratum: VIKTORIA-1 Trial of Gedatolisib Plus Fulvestrant With or Without Palbociclib in Hormone Receptor-Positive/HER2-/PIK3CA Wild-Type Advanced Breast Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19-09, CONPELAN Study.

Head & neck·2026
Same author

NanoLuc-Driven Multiplex Imaging Platforms Incorporating Novel G-series Coelenterazine Variants.

Bioconjugate chemistry·2026
Same author

Clinical and Molecular Evaluation of HER2-Low and HER2-Ultralow Breast Cancer in the Penelope-B Clinical Trial Cohort.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same author

A Real-World Efficacy and Safety of KEYNOTE-522 Regimen in Patients With Early Triple-Negative Breast Cancer.

Journal of breast cancer·2026

Related Experiment Video

Updated: Mar 17, 2026

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity
04:47

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity

Published on: October 28, 2013

10.6K

A Multichannel Bioluminescence Determination Platform for Bioassays.

Sung-Bae Kim1, Ryuichi Naganawa2

  • 1Research Institute for Environmental Management Technology, National Institute of Advanced Industrial Science and Technology (AIST), Onogawa 16-1, Tsukuba, Ibaraki, 305-8569, Japan. kimu-sb@aist.go.jp.

Methods in Molecular Biology (Clifton, N.J.)
|July 19, 2016
PubMed
Summary

This study presents a multichannel bioluminescence platform for high-throughput analysis of weak light signals. The novel system enhances efficiency and accuracy in bioassays by enabling near-simultaneous sample determination and color discrimination.

Keywords:
Assay deviceBioluminescenceCortisolSingle-chain probeSteroid hormone

More Related Videos

Flexible Measurement of Bioluminescent Reporters Using an Automated Longitudinal Luciferase Imaging Gas- and Temperature-optimized Recorder ALLIGATOR
10:33

Flexible Measurement of Bioluminescent Reporters Using an Automated Longitudinal Luciferase Imaging Gas- and Temperature-optimized Recorder ALLIGATOR

Published on: December 13, 2017

8.4K
Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
10:38

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

Published on: September 27, 2012

23.3K

Related Experiment Videos

Last Updated: Mar 17, 2026

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity
04:47

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity

Published on: October 28, 2013

10.6K
Flexible Measurement of Bioluminescent Reporters Using an Automated Longitudinal Luciferase Imaging Gas- and Temperature-optimized Recorder ALLIGATOR
10:33

Flexible Measurement of Bioluminescent Reporters Using an Automated Longitudinal Luciferase Imaging Gas- and Temperature-optimized Recorder ALLIGATOR

Published on: December 13, 2017

8.4K
Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
10:38

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

Published on: September 27, 2012

23.3K

Area of Science:

  • Biochemistry
  • Analytical Chemistry
  • Biotechnology

Background:

  • Bioluminescence assays are crucial for detecting low concentrations of analytes.
  • High-throughput screening requires efficient and accurate measurement systems.
  • Existing methods can be time-consuming and labor-intensive.

Purpose of the Study:

  • To introduce a novel multichannel bioluminescence determination platform.
  • To improve sample throughput and reduce measurement variability in bioassays.
  • To enhance the efficiency of ligand determination in multiple samples.

Main Methods:

  • Development of a multichannel bioluminescence determination platform.
  • Integration of a multichannel conveyer, optical filters, and a mirror cap.
  • Design of optical filters for easy color discrimination during assays.

Main Results:

  • The platform allows for high sample throughput determination of weak bioluminescence.
  • Reduced standard deviations were observed in measurements.
  • Near-simultaneous determination of ligands in multiple samples was achieved without sample tube replacement.
  • Efficient color discrimination during assays was enabled by the optical filter design.

Conclusions:

  • The developed platform offers significant time- and labor-efficiency for bioassays.
  • It provides a robust solution for high-throughput analysis of bioluminescent signals.
  • The system is suitable for various applications requiring sensitive and rapid ligand determination.