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Simvastatin monotherapy as a potential option for statin-associated muscle symptoms: a case report
1China Heart Institute of Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
What Is Known And Objectives:
Choosing an alternative statin is recommended when managing statin-associated muscle symptoms (SAMS) and new hydrophilic statins are often suggested. We report on a case of statin-associated muscle damage that was successfully managed by simplifying the patient's combination therapy with simvastatin-ezetimibe to simvastatin alone.
Case Summary:
The patient experienced SAMS when he was successively treated with atorvastatin, rosuvastatin, Xuezhikang capsule and combined simvastatin/ezetimibe therapy. However, the patient tolerated simvastatin therapy well even at a dose of 40 mg/day.
What Is New And Conclusion:
Our case suggests that patients with SAMS who are intolerant to a wide variety of statins may be successfully managed with simvastatin monotherapy.
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