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[Synthesis of peptides, catalyzed by ficin]
Bioorganicheskaia Khimiia
|March 1, 1989
Abstract:
Synthesis of a model peptide Z-Ala-Val-Gly-OH catalyzed by ficin in phosphate buffer was studied with water-soluble esters Z-Ala-OCH2CO-Gly-OH and Z-Ala-OCH2CO-NHC2H4SO3Na as carboxyl components. The maximal yield of the peptide was obtained at pH 8-9. The effect of temperature and concentration of reagents was studied in the model reaction.