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Updated: Mar 17, 2026

A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
Abstract:
In brief Severe (grade 3) ankle sprains with lateral ligament disruption are common in both athletes and nonathletes. Inadequate treatment leads to chronic ankle instability. Twenty-six patients underwent a 3-week treatment program using an ankle-foot orthosis (AFO), followed by a 4-week rehabilitation program. Of these patients, 96% returned to activity without restriction in about 2 1/2 months. Advantages of the AFO include ease of application, patient comfort and convenience, early ambulation, access for therapy, and rapid return to sports with a stable, asymptomatic ankle.
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