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Updated: Mar 17, 2026

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Published on: May 29, 2021
Congenital afibrinogenemia: a case report of a spontaneous hepatic hematoma
Stephanie Malaquin1, Lionel Rebibo, Cyril Chivot
1Surgical Intensive Care Unit Department of Digestive and Metabolic Surgery Department of Radiology, Amiens Picardy University Hospital INSERM U1088, University of Picardy Jules Verne, Amiens, France.
Introduction:
Afibrinogenemia is a rare coagulation disorder. Clinical features of spontaneous bleeding, bleeding after minor trauma, or after surgery have been described as well as thrombo-embolic complications. In this article, we presented the case of a 19-year old female with congenital afibrinogenemia who was admitted with a spontaneous intrahepatic hematoma.
Conclusions:
Supportive treatment including transfusion and fibrinogen administration, associated with repeated packing surgeries and selective embolization, were successfully performed.

