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Updated: Mar 17, 2026
Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture
Published on: November 25, 2025
Management of acute cholecystitis
Prabhava Bagla1, Juan C Sarria, Taylor S Riall
1aDivision of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas bDivision of General Surgery and Surgical Oncology, Department of Surgery, University of Arizona, Banner University Medical Center, Tucson, Arizona, USA.
Early surgery for acute calculous cholecystitis is recommended for most patients. Antibiotics and drainage procedures may aid management, but cholecystectomy remains the definitive treatment for this gallbladder condition.
Area of Science:
- Gastroenterology
- Surgical Management
- Hepatobiliary Diseases
Background:
- Acute calculous cholecystitis management involves controversial aspects like surgical timing and antibiotic use.
- Recent literature provides updated insights into these management strategies.
Purpose of the Study:
- To review recent studies on the timing of cholecystectomy.
- To evaluate the role of cholecystostomy tubes and antibiotics in acute cholecystitis management.
Main Methods:
- Review of recently published studies.
- Analysis of diagnostic modalities like abdominal ultrasound.
- Assessment of surgical versus nonoperative interventions.
Main Results:
- Early laparoscopic cholecystectomy (within 24-72 hours) is superior to delayed surgery for grades I and II disease.
- Percutaneous cholecystostomy and endoscopic drainage offer temporizing or definitive options for high-risk patients.
- Antibiotic necessity for uncomplicated cases remains debated.
Conclusions:
- Cholecystectomy is the definitive treatment for acute cholecystitis.
- Management should be guided by disease severity.
- Antibiotics and minimally invasive procedures serve as adjunctive therapies.
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