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Related Experiment Video

Updated: Mar 17, 2026

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
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Case 232: Amyloid β-related Angiitis.

Bardia Moosavi1, Carlos Torres1, Gerard Jansen1

  • 1From the Departments of Radiology (B.M., C.T.) and Pathology (G.J.), The Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, ON, Canada K1Y 4E9.

Radiology
|July 19, 2016
PubMed
Summary

An elderly woman experienced a fall and transient ischemic attack-like symptoms. Brain imaging revealed vasogenic edema, indicating potential neurological inflammation or injury.

Area of Science:

  • Neurology
  • Radiology

Background:

  • A 78-year-old female presented with an unwitnessed fall and transient ischemic attack (TIA)-like symptoms.
  • Medical history included memory impairment and a prior left posterior cerebral artery infarction.
  • No history of infection, malignancy, or immunosuppression was reported.

Observation:

  • Initial head computed tomography (CT) demonstrated vasogenic edema in the right temporal-parietal region.
  • Laboratory tests showed elevated C-reactive protein (29 mg/L) and erythrocyte sedimentation rate (35 mm/hr).
  • The patient experienced a generalized tonic-clonic seizure shortly after admission.

Findings:

  • Magnetic resonance (MR) imaging of the brain was performed for further evaluation.
  • The findings are suggestive of an underlying inflammatory or ischemic neurological process.

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  • The combination of symptoms and imaging findings warrants further investigation.

    • Implications:

    • This case highlights the importance of comprehensive neuroimaging and laboratory work-up in elderly patients with neurological deficits and falls.
    • Understanding the etiology of vasogenic edema in this context is crucial for appropriate management.
    • Further investigation may reveal an underlying condition contributing to recurrent neurological events.