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Updated: Mar 17, 2026

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue

Published on: November 27, 2017

Muscle ultrasound.

Sigrid Pillen¹, Andrea Boon², Nens Van Alfen³

¹Department of Sleep Medicine, Kempenhaeghe Expertise Center for Epileptology, Sleep Medicine and Neurocognition, Heeze, The Netherlands.

Handbook of Clinical Neurology

|July 20, 2016

Summary

Muscle ultrasound offers noninvasive, radiation-free neuromuscular imaging for diagnosing conditions like pediatric neuromuscular disease and amyotrophic lateral sclerosis. This technique can guide treatment and potentially replace more invasive diagnostic procedures.

Keywords:

Doppler imaging Heckmatt scale congenital myopathy dystrophy echogenicity fasciculations motor neuron disease muscle ultrasound myositis quantitative

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Last Updated: Mar 17, 2026

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue

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Published on: November 27, 2017

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Published on: August 25, 2022

Area of Science:

Neurology
Radiology
Musculoskeletal Imaging

Background:

Muscle ultrasound is a noninvasive, radiation-free imaging technique.
It offers point-of-care neuromuscular assessment capabilities.
It has diverse applications in evaluating muscle function and pathology.

Purpose of the Study:

To provide an overview of muscle ultrasound fundamentals.
To detail clinical applications in neuromuscular disorders.
To discuss the validation of muscle ultrasound as a diagnostic tool.

Main Methods:

Review of existing literature and clinical applications.
Discussion of specific techniques like Tissue Doppler imaging.
Emphasis on computer-assisted quantification for diagnosis.

Main Results:

Muscle ultrasound can identify abnormal muscle movements (fasciculations) and trauma.
It accurately measures physiological parameters like pennation angle.
It improves accuracy in challenging electrodiagnostic studies (e.g., diaphragm EMG).

Conclusions:

Muscle ultrasound demonstrates high sensitivity and specificity in diagnosing neuromuscular diseases.
It serves as a valuable addition to existing diagnostic methods.
It can function as a first-line screening tool, potentially avoiding invasive procedures.