Related Experiment Video
Updated: Mar 17, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Accessible weight loss: Adapting a lifestyle intervention for adults with impaired mobility
Andrea C Betts1, Katherine Froehlich-Grobe2
1Baylor Institute for Rehabilitation, Dallas, TX, USA; Division of Health Promotion and Behavioral Sciences, University of Texas School of Public Health, Dallas Regional Campus, USA.
Background:
Despite disparities in obesity between those with and without disability, there is limited evidence to guide weight loss intervention in people with impaired mobility (IM), particularly those with severe impairments.
Objective:
Examine the usability, feasibility, and effectiveness of adapting an existing evidence-based weight loss program for people with IM.
Methods:
In this single-group pre-test post-test pilot study, 10 overweight or obese individuals with permanent IM (e.g. spinal cord injury, spina bifida, osteoarthritis) participated in a 20-week modification of the DPP Group Lifestyle Balance™ (DPP GLB) program, a group-based adaptation of the Diabetes Prevention Program (DPP). Fifteen conference calls encouraged reducing calorie and fat intake and increasing exercise through self-monitoring and problem solving. We defined feasibility as retention and engagement, usability as participants' program satisfaction ratings, and effectiveness as physiological and psychosocial change measured on three occasions over 20 weeks. Analytic methods included basic descriptive statistics (feasibility and usability) and repeated measures ANOVA (effectiveness).
Results:
The program retained 70% of participants. These individuals attended an average of 79.3% of conference calls and self-monitored more than half of the weeks. Participants rated the program highly, with mean overall scores of 6.3 ± 0.3 and 6.2 ± 0.6 out of 7 on helpfulness and satisfaction scales, respectively. Program completers experienced a significant mean weight loss of 8.86 ± 8.37 kg (p = 0.024), or 7.4% of their start weight, and significantly reduced their BMI.
Conclusions:
An adapted version of the DPP GLB is a feasible, usable, and potentially effective intervention for promoting weight loss among persons with IM.
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