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Updated: Mar 17, 2026

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Optical Coherence Tomography Angiography Findings in Coats' Disease
Background And Objective:
To describe optical coherence tomography angiography (OCTA) findings in patients with unilateral Coats' disease.
Patients And Methods:
Retrospective, observational case series of four patients with unilateral Coats' disease who underwent bilateral OCTA imaging.
Results:
Bilateral macular OCTA findings of eight eyes are described. An abnormal foveal avascular zone (FAZ) with inner retinal vessels traversing the avascular zone in the superficial capillary plexus was visible on OCTA in the affected eye of all four patients. A similarly abnormal FAZ was noted on OCTA in the clinically normal fellow eye in two of the four patients (50%).
Conclusion:
OCTA may demonstrate an abnormal foveal avascular zone in both the affected eye and the clinically unaffected fellow eye, suggesting widespread pathology of the retinal vasculature in Coats' disease. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:632-635.].
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