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Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II

Si-Cheng Liang1,2,3, Guang-Bo Ge1, Yang-Liu Xia1

  • 1a Laboratory of Pharmaceutical Resource Discovery , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian , China.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|July 21, 2016
PubMed

Keywords:
8-O-methyldaphnetinCOMT inhibitorDaphnetinPhase II metaboliteligand–protein interactionstructural modification

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