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Related Experiment Video

Updated: Mar 17, 2026

Robotic Enucleation of Esophageal Leiomyoma

Robotic Enucleation of Esophageal Leiomyoma

Published on: February 20, 2026

Recurrent renal giant leiomyosarcoma.

Salih Erpulat Öziş¹, Kamil Gülpınar¹, Zafer Şahlı¹

¹Department of General Surgery, Ufuk University School of Medicine, Ankara, Turkey.

Ulusal Cerrahi Dergisi

|July 21, 2016

Summary

Primary renal leiomyosarcomas are rare aggressive tumors. This case highlights a patient whose low-grade renal leiomyosarcoma transformed into a high-grade tumor within a year, emphasizing diagnostic challenges.

Keywords:

Leiomyosarcoma kidney recurrence

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Area of Science:

Oncology
Pathology
Radiology

Background:

Primary renal leiomyosarcomas are rare, aggressive malignancies, representing 1-2% of adult malignant renal tumors.
Despite being the most common renal sarcoma subtype (50-60%), clinical and radiological data on renal leiomyosarcoma remain limited.
Distinguishing renal leiomyosarcoma from renal cell carcinoma based solely on imaging is challenging due to non-specific radiological features.

Observation:

A 74-year-old female presented with a large abdominal mass.
Previous imaging in 2007 identified a renal mass initially diagnosed as renal cell carcinoma but pathologically confirmed as low-grade renal leiomyosarcoma.
In 2012, a significantly larger retroperitoneal mass was excised and diagnosed as high-grade leiomyosarcoma.

Findings:

The patient experienced a rapid progression from a low-grade renal leiomyosarcoma to a high-grade retroperitoneal mass within approximately one year.
This case demonstrates the potential for aggressive transformation in primary renal leiomyosarcomas.
The initial misdiagnosis highlights the limitations of imaging in differentiating renal tumors.

Implications:

This case underscores the importance of thorough pathological examination for accurate diagnosis of renal masses.
It suggests the need for vigilant follow-up of patients diagnosed with renal leiomyosarcoma due to the risk of aggressive transformation.
Further research into the biological behavior and optimal management of renal leiomyosarcomas is warranted.