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Updated: Mar 17, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
A Case of Erythroderma Secondary to Hypereosinophilia
Mohammed Shafi Abdulsalam1, Hari Chandana Ghanta2, Prabu Pandurangan3
1Post Graduate Student, Department of Internal Medicine, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India .
Abstract:
Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRα) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare.
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