Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia.

Annals of oncology : official journal of the European Society for Medical Oncology·2019
Same author

Phase II trial of galiximab (anti-CD80 monoclonal antibody) plus rituximab (CALGB 50402): Follicular Lymphoma International Prognostic Index (FLIPI) score is predictive of upfront immunotherapy responsiveness.

Annals of oncology : official journal of the European Society for Medical Oncology·2018
Same author

Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL.

Leukemia·2017
Same author

PLCG2 C2 domain mutations co-occur with BTK and PLCG2 resistance mutations in chronic lymphocytic leukemia undergoing ibrutinib treatment.

Leukemia·2017
Same author

The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia.

Leukemia·2017
Same author

Ibrutinib in previously treated chronic lymphocytic leukemia patients with autoimmune cytopenias in the RESONATE study.

Blood cancer journal·2017
Same journal

Injury surveillance during the 2024 under 20s Men's European Field Lacrosse Championships.

The Physician and sportsmedicine·2026
Same journal

Understanding health insurance and the delay in care for partial meniscectomies: a comparison between public and private coverage.

The Physician and sportsmedicine·2026
Same journal

Injury incidence and risk factors in youth American football versus soccer: a national emergency department analysis.

The Physician and sportsmedicine·2026
Same journal

Links between concussion history, hypertension, and hypertension contributing factors among adolescent football athletes.

The Physician and sportsmedicine·2026
Same journal

Core muscle endurance and balance as predictors of lateral ankle sprain in adolescent team-sport athletes: a prospective cohort study.

The Physician and sportsmedicine·2026
Same journal

Impact of Achilles tendon rupture on performance and career outcomes in NFL players: a matched cohort study.

The Physician and sportsmedicine·2026
See all related articles

Related Experiment Video

Updated: Mar 17, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.4K

Frontal Astrocytoma.

D J Leizman, G M Mosley, J C Byrd

    The Physician and Sportsmedicine
    |July 21, 2016
    PubMed
    Summary
    This summary is machine-generated.

    A frontal lobe tumor in a young runner caused exertional syncope by prolonging the QTC interval and inducing ventricular tachycardia. Surgical removal of the astrocytoma resolved the cardiac abnormality and fainting episodes.

    More Related Videos

    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
    13:12

    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

    Published on: August 12, 2019

    46.7K
    Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
    10:13

    Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

    Published on: August 12, 2014

    14.0K

    Related Experiment Videos

    Last Updated: Mar 17, 2026

    Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
    09:53

    Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

    Published on: July 5, 2021

    4.4K
    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
    13:12

    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

    Published on: August 12, 2019

    46.7K
    Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
    10:13

    Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

    Published on: August 12, 2014

    14.0K

    Area of Science:

    • Neuroscience
    • Cardiology
    • Oncology

    Background:

    • Exertional syncope can be a symptom of serious underlying conditions.
    • Prolonged QTC interval on electrocardiogram (ECG) is associated with increased risk of ventricular arrhythmias.
    • Autonomic nervous system dysfunction can influence cardiac electrophysiology.

    Purpose of the Study:

    • To investigate the potential link between a frontal lobe tumor and exertional syncope.
    • To determine the mechanism by which a brain lesion may affect cardiac function.
    • To report the resolution of syncope and ECG abnormalities after tumor resection.

    Main Methods:

    • Case report of a 27-year-old recreational runner with recurrent exertional syncope.
    • Diagnostic workup included exercise electrocardiogram (ECG), electroencephalogram (EEG), and magnetic resonance imaging (MRI).
    • Surgical excision of the identified frontal astrocytoma.

    Main Results:

    • The patient experienced exertional syncope twice within 6 months.
    • Exercise ECG revealed abnormal QTC interval prolongation.
    • EEG and MRI confirmed a right-hemisphere frontal astrocytoma.
    • Post-surgical excision, the ECG abnormality resolved, and syncope ceased.

    Conclusions:

    • Frontal lobe tumors can potentially cause cardiac arrhythmias, such as prolonged QTC interval and ventricular tachycardia, through autonomic pathways.
    • This case highlights a rare but significant neurological cause of exertional syncope.
    • Surgical intervention for the brain tumor led to the resolution of both the cardiac electrophysiological abnormality and the clinical symptoms.