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Updated: Mar 17, 2026

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
Published on: June 12, 2021
Antigen-Addicted T Cell Reserves Trickle Charge the Frontline Killers
Vandana Kalia1, Surojit Sarkar2
1Department of Pediatrics, Division of Hematology and Oncology, University of Washington School of Medicine, Seattle, WA 98195, and Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.
Abstract:
Highly active killer T cells mediate a stable standoff during controlled persistent infections. In this issue of Immunity, Robey and colleagues describe a unique antigen-addicted T cell population bearing characteristics of both effector and memory CD8(+) T cells that provides a continuous supply of potent killer T cells to curb Toxoplasma gondii growth during latency.
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