Oncocytic cystic lesions of the upper respiratory tract

Oncocytic cystic lesions in the larynx comprise an uncommon but pathologically well-defined group, whereas only one case has been reported in the nasopharynx. The laryngeal cysts generally originate from the ventricle and occur in an older age group. Hoarseness is the most common clinical manifestation, with lesions appearing as polypoid masses. Their pathogenesis is considered to be the result of oncocytic metaplasia, apparently related to aging of cells in the seromucinous gland and ducts. The cystic dilatation is probably due to an obstructive phenomenon. Complete endoscopic removal is the treatment of choice. Examples of these lesions in the larynx and in the nasopharyngeal mucosa are described.