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Laboratory tests as short-term correlates of stroke
Trevor Sughrue1,2, Michael A Swiernik1, Yang Huang1
1Kaiser Permanente Southern California, San Diego, CA, USA.
BMC Neurology
|July 22, 2016
Summary
Electronic health records reveal dozens of lab tests correlating with future stroke risk. This study identifies 38 key tests for short-term stroke prediction, aiding early intervention strategies.
Area of Science:
- Biomedical Informatics
- Neurology
- Clinical Pathology
Background:
- Electronic health records (EHRs) offer novel avenues for predicting patient outcomes.
- Utilizing EHR data, this study investigates the link between laboratory tests and stroke incidence.
Purpose of the Study:
- To assess the correlation between various laboratory tests and the future occurrence of stroke.
- To identify specific laboratory markers with prognostic value for stroke.
Main Methods:
- Analysis of EHR data from 2.4 million individuals over two years.
- Inclusion of 26,964 stroke diagnoses in the dataset.
- Application of Cox regression analysis to evaluate 1796 laboratory tests for stroke correlation.
Main Results:
- Identification of 38 laboratory tests demonstrating significant short-term (two-year) prognostic value for stroke.
- Compilation of Kaplan-Meier survival curves and relative risk ratios for each identified test.
Conclusions:
- A significant number of laboratory tests serve as effective short-term predictors of stroke.
- Findings support the use of routine laboratory data for early stroke risk assessment.
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