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Set7 mediated interactions regulate transcriptional networks in embryonic stem cells

Natasha K Tuano1, Jun Okabe2,3, Mark Ziemann1,4

  • 1Epigenetics in Human Health and Disease Laboratory, Baker IDI Heart and Diabetes Institute, The Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia.

Nucleic Acids Research
|July 22, 2016
PubMed
Summary

Set7 enzyme activity is crucial for embryonic stem cell differentiation, regulating gene expression through histone methylation. Its increased expression, controlled by Oct4 and Sox2, impacts smooth muscle gene networks.

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