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Tumour necrosis factor in neonatal listeriosis: a case report
E Girardin1, M Berner, G E Grau
1Department of Paediatrics and Genetics, Hôpital Cantonal Universitaire de Genève, Switzerland.
European Journal of Pediatrics
|June 1, 1989
Abstract:
A newborn with fatal neonatal listeriosis developed septic shock, neutropenia, thrombocytopenia and profound hypoxaemia due to severe pulmonary hypertension. Tumour necrosis factor alpha, interleukin-1-beta and interferon-gamma serum concentrations were markedly elevated, suggesting the participation of these cytokines in the aetiopathogenesis of shock induced by Listeria monocytogenes in the neonate.