Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Mar 17, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

Decrease in rate of multiple sclerosis-related hospitalizations in Portugal.

Marta Pereira¹, Dimitra Lambrelli¹, Sreeram V Ramagopalan¹

¹Real-World Evidence, Evidera, London, W6 8DL, UK.

|July 22, 2016

Summary

Multiple sclerosis (MS) hospitalizations in Portugal significantly decreased by 44% between 2008 and 2013. This trend aligns with global observations and the introduction of new MS therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

R WE ready for reimbursement? A round-up of developments in real-world evidence relating to health technology assessment: part 27.

Journal of comparative effectiveness research·2026

Same author

Access in all areas? A round-up of developments in market access and health technology assessment: part 15.

Journal of comparative effectiveness research·2026

Same author

Most-Favored-Nation pricing meets Joint Clinical Assessment: early evidence of compounding pressure on European drug launches.

Journal of comparative effectiveness research·2026

Same author

Access in all areas? A round-up of developments in market access and health technology assessment: first Joint Clinical Assessment report released.

Journal of comparative effectiveness research·2026

Same author

Improved real-world outcomes of patients with acute promyelocytic leukaemia treated with first-line arsenic trioxide in specialized centres in Portugal through a 24/7 phone-based referral.

British journal of haematology·2026

Same author

Infection following foot and ankle surgery : a subanalysis of data captured from the UK Foot and Ankle Thromboembolism (FATE) audit.

The bone & joint journal·2026

Area of Science:

Neurology
Epidemiology
Health Services Research

Background:

Multiple sclerosis (MS) is a chronic neurological disease impacting healthcare systems globally.
Temporal trends in MS-related hospitalizations vary by region.
Understanding hospitalization rates is crucial for resource allocation and patient care.

Purpose of the Study:

To investigate the rate of multiple sclerosis (MS)-related hospitalizations in Portugal.
To assess temporal changes in these hospitalization rates.
To correlate observed trends with the availability of new MS therapies.

Main Methods:

Utilized data from the Portuguese National Discharge Registry.
Analyzed hospitalization rates per 100 person-years between 2008 and 2013.

Keywords:

epidemiology hospitalizations multiple sclerosis

Related Experiment Videos

Last Updated: Mar 17, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

Calculated percentage change and confidence intervals for hospitalization rates.

Main Results:

A 44% decrease in MS-related hospitalizations was observed from 2008 to 2013.
Hospitalization rates declined from 15.9/100 person-years in 2008 to 8.9/100 person-years in 2013.
This decline aligns with trends seen in other countries.

Conclusions:

MS hospitalization rates in Portugal have significantly decreased.
The observed decrease coincides with the introduction of new MS therapies.
These findings suggest improved disease management and treatment efficacy impacting healthcare utilization.