Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A developmental switch in sea urchin U1 RNA.

M A Nash1, S Sakallah, C Santiago

  • 1Department of Chemistry, Florida State University, Tallahassee 32306.

Developmental Biology
|August 1, 1989
PubMed
Summary

Sea urchin U1 RNA sequences change during development. Egg U1 RNA differs between species, but embryonic U1 RNA becomes identical, originating from genes not used in adult tissues.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Survival Benefits Outweigh Germline Competition Costs in Kin Chimeras.

bioRxiv : the preprint server for biology·2026
Same author

Benchmarking variability in semantic segmentation in minimally invasive abdominal surgery.

International journal of computer assisted radiology and surgery·2026
Same author

Molecular characterization of an adhesion GPCR signal transduction.

bioRxiv : the preprint server for biology·2025
Same author

[Smell and taste disorders in Spanish patients with mild COVID-19].

Neurologia (Barcelona, Spain)·2024
Same author

Uncovering and engineering the mechanical properties of the adhesion GPCR ADGRG1 GAIN domain.

bioRxiv : the preprint server for biology·2023
Same author

[The perforator flap of ipsilateral nasolabial sulcus used to repair the defect after the eradication of nasal vestibular squamous cell carcinoma].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2023

Area of Science:

  • Molecular Biology
  • Developmental Biology
  • Marine Biology

Background:

  • U1 RNA is a small nuclear ribonucleoprotein essential for pre-mRNA splicing.
  • Gene expression patterns change significantly during embryonic development.
  • Sea urchins are model organisms for studying early development and gene regulation.

Purpose of the Study:

  • To determine and compare the sequences of U1 RNA in sea urchin eggs and embryos.
  • To investigate developmental changes in U1 RNA sequences within and between species.
  • To identify the gene origins of U1 RNA during different developmental stages.

Main Methods:

  • RNA sequencing to determine U1 RNA sequences.
  • Comparative sequence analysis between different developmental stages and species.
  • Analysis of gene expression patterns for U1 RNA genes.

Main Results:

  • U1 RNA sequences were determined for *Lytechinus variegatus* and *Strongylocentrotus purpuratus* eggs and embryos.
  • U1 RNA sequences in eggs differed by two nucleotides between the two species.
  • U1 RNA sequences in late embryos and somatic tissues were identical between the two species.
  • Egg and early embryonic U1 RNA are primarily derived from tandemly repeated gene sets.
  • These tandemly repeated genes are not expressed in somatic tissues.

Conclusions:

  • U1 RNA sequences undergo significant changes during sea urchin development.
  • Developmental regulation of U1 RNA involves differential expression of gene sets.
  • The conserved U1 RNA in later stages suggests a critical role in maintaining somatic cell function.

Related Experiment Videos