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Hyponatremia associated with preeclampsia.

Armin S Razavi1, Stephen T Chasen1, Ritu Gyawali1

  • 1.

Journal of Perinatal Medicine
|July 22, 2016
PubMed
Summary

Hyponatremia (low sodium) affects nearly 10% of preeclampsia patients, being more common in severe cases and twin pregnancies. Monitoring serum sodium is recommended for these high-risk groups.

Keywords:
Hypertensionhyponatremiapreeclampsiapregnancy

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Clinical Chemistry

Background:

  • Preeclampsia is a serious pregnancy complication characterized by high blood pressure.
  • Hyponatremia, or low serum sodium, can occur in various medical conditions, but its prevalence in preeclampsia is not well-established.

Purpose of the Study:

  • To determine the frequency of hyponatremia in patients with preeclampsia.
  • To identify clinical factors associated with hyponatremia in this population.

Main Methods:

  • A descriptive study analyzed data from 332 pregnancies complicated by preeclampsia between 2013 and 2014.
  • Hyponatremia was defined as serum sodium <130 mEq/L, considering pregnancy-related sodium level changes.
  • Preeclampsia with and without severe features was classified according to established guidelines.

Main Results:

  • Hyponatremia was observed in 9.7% of patients with preeclampsia.
  • Patients with preeclampsia with severe features had a higher incidence of hyponatremia compared to those without severe features (P<0.001).
  • Hyponatremia was also more frequent in twin gestations (P=0.001) and older women (P=0.017).

Conclusions:

  • Hyponatremia is a notable finding in preeclampsia, particularly in severe cases and twin pregnancies.
  • Serum sodium monitoring is advised for pregnant individuals with preeclampsia, especially those with severe features or multiple gestations.