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Updated: Mar 17, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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ISCEV standard for clinical visual evoked potentials: (2016 update).

J Vernon Odom1, Michael Bach2, Mitchell Brigell3

  • 1West Virginia University Eye Institute, P.O. Box 9193, Morgantown, WV, 26506-9193, USA. jodom@wvu.edu.

Documenta Ophthalmologica. Advances in Ophthalmology
|July 23, 2016
PubMed
Summary

This updated standard for visual evoked potentials (VEPs) ensures reliable clinical testing. It harmonizes VEP protocols with other international standards for consistent visual system assessment.

Keywords:
Flash visual evoked potentialPattern onset/offsetPattern-reversal visual evoked potentialStandardVisual evoked potential

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Clinical Electrophysiology

Background:

  • Visual evoked potentials (VEPs) are crucial for assessing visual system function.
  • Previous ISCEV standards for VEP testing require updating to reflect technological advancements.
  • Harmonizing VEP protocols with other ISCEV standards enhances consistency in clinical practice.

Purpose of the Study:

  • To update the International Society for Clinical Electrophysiology of Vision (ISCEV) standard for clinical VEP testing.
  • To supersede the 2009 ISCEV VEP standard.
  • To ensure consistency and accuracy in VEP diagnostic procedures.

Main Methods:

  • The revised standard focuses on core clinical information using specific stimulus and recording conditions.
  • Includes pattern-reversal VEPs (1° and 0.25° checks), pattern onset/offset VEPs (1° and 0.25° checks), and flash VEPs (≥20° visual field).
  • Standard protocols utilize a single recording channel with a midline occipital electrode for pre-chiasmal assessment.

Main Results:

  • Acknowledges diverse pattern stimulus technologies, emphasizing the need for consistent luminance during pattern reversal/onset/offset.
  • Standardized protocols are designed for broad applicability in global clinical electrophysiology laboratories.
  • Distinguishes between standard protocols for anterior visual pathway assessment and extended protocols for post-chiasmal lesions.

Conclusions:

  • The updated ISCEV standard provides a robust framework for clinical VEP testing.
  • Ensures reliable diagnostic information regarding the functional integrity of the visual system.
  • Facilitates international consistency in VEP testing for various visual pathway assessments.