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Antibiotic delivery by nanobioceramics.

Ts Sampath Kumar1, K Madhumathi1

  • 1Medical Materials Laboratory, Department of Metallurgical & Materials Engineering, Indian Institute of Technology Madras, Chennai 600036, India.

Therapeutic Delivery
|July 23, 2016
PubMed
Summary

Nanotechnology offers advanced bioceramic nanoparticles for targeted drug delivery in orthopedics. These nanobioceramics show promise for treating bone infections by enabling localized and effective medication release.

Keywords:
antibioticsbioactive glassbioceramicscalcium phosphateion substitutionslocal drug deliverynanomaterialssilicatitania

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Drug Delivery Systems

Background:

  • Bioceramics are inorganic biomaterials widely used as bone substitutes.
  • Nanotechnology has significantly advanced drug delivery applications.
  • Bioceramics are being explored as carriers for various therapeutic agents.

Purpose of the Study:

  • To review the development and applications of nanobioceramics in drug delivery.
  • To highlight the potential of nanobioceramics for treating bone infections.

Main Methods:

  • Review of scientific literature on nanobioceramics for drug delivery.
  • Focus on bioceramic nanoparticles as drug carriers.

Main Results:

  • Bioceramic nanoparticles offer advantages over polymers, including bioactivity, stability, and tunable biodegradability.
  • Local drug delivery using bioceramics in orthopedics provides an efficient and safe alternative to systemic delivery.
  • Nanobioceramics are effective carriers for antibiotics, anti-osteoporotic, and anticancer drugs.

Conclusions:

  • Nanobioceramics represent a promising platform for localized drug delivery in orthopedic applications.
  • Their properties make them ideal for developing advanced systems to combat bone infections.