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Multiple Periprosthetic Joint Infections: Evidence for Decreasing Prevalence
John P Haverstock1, Lyndsa E Somerville1, Douglas D Naudie1
1Division of Orthopedic Surgery, London Health Sciences Centre, University Hospital, Western University, London, Ontario, Canada.
The Journal of Arthroplasty
|July 23, 2016
Summary
The prevalence of multiple periprosthetic joint infections (MPJIs) is uncommon, with 6.3% of at-risk patients developing a second infection. Some second infections were hematogenous, while others were unrelated to the initial joint replacement infection.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Epidemiology
Background:
- Multiple periprosthetic joint infections (MPJIs) are infrequent occurrences in orthopedic surgery.
- Understanding the incidence of secondary infections is crucial for patient management and outcomes.
Purpose of the Study:
- To determine the prevalence of developing a second-site periprosthetic joint infection (MPJI).
- To analyze the characteristics and outcomes of patients with secondary MPJIs.
Main Methods:
- Retrospective review of an institutional arthroplasty database.
- Chart review for patients who developed a second periprosthetic joint infection to identify pathogen, timing, comorbidities, and treatment outcomes.
Main Results:
- A total of 6.3% (13 of 206) of at-risk patients developed a second periprosthetic joint infection.
- Six secondary infections were hematogenous, occurring during treatment of the index infection.
- Seven secondary infections were unrelated to the initial infection; outcomes included suppressive antibiotics or successful infection clearance.
Conclusions:
- The incidence of multiple periprosthetic joint infections (MPJIs) has shown a decrease compared to historical data.
- Further research may elucidate specific risk factors and optimal management strategies for secondary MPJIs.
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