Related Experiment Video
Updated: Mar 17, 2026
08:15
Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Published on: January 31, 2020
9.2K
To whom is HIV pre-exposure prophylaxis proposed?
Oskar Ayerdi-Aguirrebengoa1, Mar Vera-García2, Teresa Puerta-López2
1Servicio de Urgencias, Hospital Fundación Jiménez Díaz, Madrid, España; Unidad de ITS/VIH, Centro Sanitario Sandoval IdISSC, Madrid, España.
Enfermedades Infecciosas Y Microbiologia Clinica
|July 23, 2016
Summary
Recent HIV infections primarily occurred in men who have sex with men aged 20-39. Many engaged in high-risk behaviors, highlighting the need for targeted HIV Pre-Exposure Prophylaxis (PrEP) identification.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- HIV Pre-Exposure Prophylaxis (PrEP) involves antiretroviral drugs for HIV-negative individuals at high risk.
- Understanding recent HIV seroconverters is crucial for identifying optimal PrEP candidates.
Purpose of the Study:
- To describe characteristics of individuals recently diagnosed with HIV.
- To identify profiles of appropriate candidates for HIV Pre-Exposure Prophylaxis (PrEP).
Main Methods:
- A descriptive study analyzed HIV patients diagnosed in 2014 with prior negative serology.
- Data collected included sociodemographic, behavioral, and clinical features.
- Testing for other sexually transmitted infections was also performed.
Main Results:
- The study included 61 recent HIV seroconverters, predominantly men who have sex with men (98.4%) aged 20-39 (88.5%).
- High prevalence of sexually transmitted infections (80.3%) was observed.
- Multiple unprotected sexual practices (82.7%) and recreational drug use (87%) were common.
Conclusions:
- Identifying risk factors in HIV-negative individuals is key to selecting appropriate PrEP candidates.
- This profile can inform targeted HIV prevention strategies.
Keywords:
Human immunodeficiency virusPre-exposure prophylaxisProfilaxis pre-exposiciónRecent seroconvertorSeroconvertores recientesVirus de la inmunodeficiencia humanaMore Related Videos
Related Concept Videos
01:10Retrovirus Life Cycles
50.3K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
50.3K
01:26Sexually Transmitted Infections
1.5K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.5K
01:25Transmission-based Precautions II: Airborne and Protective Environment
2.1K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
2.1K
01:17Transmission-based Precautions I: Contact, Enteric, and Droplets
5.0K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
5.0K
01:29Pulmonary Tuberculosis I
1.2K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.2K
01:26Standard Precaution
3.3K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
3.3K