Early Repolarization Syndrome; Mechanistic Theories and Clinical Correlates

Ben N Mercer1, Gordon A Begg1, Stephen P Page2

  • 1West Yorkshire Arrhythmia Service, Leeds General Infirmary Leeds, UK.

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The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
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Depolarizing blockers act on skeletal muscle fibers' membranes and induce their depolarization. Most depolarizing blockers have two quaternary N+ atoms that bind the nicotinic acetylcholine receptors and cause neuromuscular blockade within minutes.
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