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Published on: August 1, 2019
Age Is the Only Predictor of Poor Bowel Preparation in the Hospitalized Patient
Julia McNabb-Baltar1, Alastair Dorreen2, Hisham Al Dhahab3
1Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Insights
Advanced age is the sole predictor of poor bowel preparation in hospitalized patients undergoing colonoscopy. This finding impacts strategies for optimizing colonoscopy success rates in elderly individuals.
Area of Science:
- Gastroenterology
- Clinical Medicine
- Health Services Research
Background:
- Adequate bowel preparation is crucial for successful colonoscopy.
- Poor bowel preparation can lead to missed lesions and repeat procedures.
- Identifying predictors of poor preparation in hospitalized patients is essential for improving outcomes.
Purpose of the Study:
- To identify key variables associated with poor inpatient bowel preparation for colonoscopy.
- To determine independent predictors of inadequate bowel cleansing in a hospitalized population.
Main Methods:
- Retrospective analysis of inpatient colonoscopy records from January 2010 to December 2011.
- Univariable and multivariable logistic regression models were used to assess predictor effects.
- Variables included demographics, medication burden, comorbidities, surgical history, and preparation details.
Main Results:
- Out of 244 patients, 34% had poor bowel preparation.
- Cecal intubation rates were significantly lower in patients with poor preparation (65.9%) compared to good preparation (89.9%).
- Advancing age was the only independent predictor of poor bowel preparation (OR = 1.026, p = 0.008).
Conclusions:
- Age is the primary independent risk factor for poor bowel preparation in hospitalized patients.
- Targeted strategies for elderly patients may improve bowel preparation quality.
- Further research could explore interventions to mitigate age-related risks for better colonoscopy efficacy.
Abstract:
We examine the impact of key variables on the likelihood of inpatient poor bowel preparation for colonoscopy. Records of inpatients that underwent colonoscopy at our institution between January 2010 and December 2011 were retrospectively extracted. Univariable and multivariable logistic regression models were fitted to assess the effect of clinical variables on the odds of poor preparation. Tested predictors included age; gender; use of narcotics; heavy medication burden; comorbidities; history of previous abdominal surgery; neurological disorder; product used for bowel preparation, whether or not the bowel regimen was given as split or standard dose; and time of endoscopy. Overall, 244 patients were assessed including 83 (34.0%, 95% CI: 28.1-39.9%) with poor bowel preparation. Cecal intubation was achieved in 81.1% of patients (95% CI: 76.2-86.0%). When stratified by quality of bowel preparation, cecal intubation was achieved in only 65.9% (95% CI: 60.0-71.9%) of patients with poor bowel preparation and 89.9% (95% CI: 86.1-93.7%) of patient with good bowel preparation. In multivariate logistic regression analysis, only advancing age was an independent predictor of poor bowel preparation (OR = 1.026, CI: 1.006 to 1.045, and p = 0.008). Age is the only independent predictor of poor bowel preparation amongst hospitalized patients.
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