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Fractures: Bone Repair

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...

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Related Experiment Video

Updated: Jul 11, 2026

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects

Published on: December 10, 2021

Four-Strand Core Suture Improves Flexor Tendon Repair Compared to Two-Strand Technique in a Rabbit Model.

Alice Wichelhaus¹, Sascha Tobias Beyersdoerfer¹, Brigitte Vollmar²

¹Abteilung für Unfall-, Hand- und Wiederherstellungschirurgie, Chirurgische Universitätsklinik Rostock, Schillingallee 35, 18055 Rostock, Germany.

Biomed Research International

|July 23, 2016

Summary

A 4-strand suture technique for flexor tendon repair significantly reduces gap formation between tendon ends. While a 2-strand technique may lead to fewer adhesions, the 4-strand method promotes better overall tendon healing.

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Area of Science:

Orthopedic Surgery
Biomaterials Science
Regenerative Medicine

Background:

Peritendinous adhesions are a common complication following intrasynovial flexor tendon repair.
The amount of suture material used can influence the healing process and adhesion formation.

Purpose of the Study:

To investigate the impact of suture material quantity on peritendinous adhesion formation in flexor tendon repairs.
To compare the efficacy of 2-strand versus 4-strand core suture techniques in promoting tendon healing.

Main Methods:

Flexor tendons in rabbit hind legs were repaired using either a 2-strand or 4-strand core suture technique.
Tendons were harvested at 3 and 8 weeks post-repair for histological analysis.
Measurements included gap formation, peritendinous changes, and inflammatory responses.

Main Results:

A 4-strand core suture significantly reduced gap formation between tendon ends.
The 2-strand core suture showed a trend towards less adhesion formation.
Increased suture material initially elevated leukocyte infiltration and myofibroblast formation, with inflammation decreasing over time.

Conclusions:

A 4-strand core suture repair results in superior tendon healing with reduced diastasis.
Despite an initial inflammatory response, the 4-strand technique offers significant benefits for flexor tendon repair outcomes.