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Related Concept Videos

Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

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Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
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Increased Body Temperature01:25

Increased Body Temperature

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Thermoregulation01:26

Thermoregulation

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The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
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Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
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Body Temperature01:25

Body Temperature

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The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
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Body Temperature01:07

Body Temperature

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Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
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Related Experiment Video

Updated: Mar 17, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
07:56

Protocol for Long Duration Whole Body Hyperthermia in Mice

Published on: August 25, 2012

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Hyperthermia: New Thoughts on an Old Problem.

R W Hubbard, L E Armstrong, M D Bracker

    The Physician and Sportsmedicine
    |July 23, 2016
    PubMed
    Summary
    This summary is machine-generated.

    This review covers heat illnesses like heat exhaustion and heatstroke, finding 15°C water cooling as effective as ice water. An energy depletion model explains exercise-induced hyperthermia

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    Area of Science:

    • Sports Medicine
    • Environmental Physiology
    • Emergency Medicine

    Background:

    • Common heat illnesses include heat syncope, heat exhaustion, and exertional heatstroke.
    • Effective and practical treatment strategies for exertional heatstroke are crucial for patient outcomes.

    Purpose of the Study:

    • To review the causes and treatment of common heat illnesses.
    • To compare the effectiveness of different cooling methods for exertional heatstroke.
    • To present the energy depletion model for exercise-induced hyperthermia.

    Main Methods:

    • Literature review of heat illness causes and treatments.
    • Comparative analysis of cooling methods: ice water versus 15°C water.
    • Presentation and discussion of the energy depletion model.

    Main Results:

    • Cooling exertional heatstroke victims with 15°C water is as effective as using ice water.
    • The 15°C water method is more practical for clinical application.
    • The energy depletion model illustrates the cycle leading to reduced exercise/heat tolerance and potential mortality.

    Conclusions:

    • 15°C water immersion is a practical and effective treatment for exertional heatstroke.
    • The energy depletion model highlights persistent cellular/metabolic deficits post-cooling in exercise-induced hyperthermia.