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Intestinal Failure: New Definition and Clinical Implications.

Matthew Kappus1, Sarah Diamond2, Ryan T Hurt3

  • 1Department of Medicine, Duke University, Durham, NC, USA. Matthew.kappus@duke.edu.

Current Gastroenterology Reports
|July 23, 2016
PubMed
Summary

Intestinal failure (IF) is a condition where the body cannot absorb enough nutrients. This review clarifies IF definitions, crucial for consistent patient recognition and management.

Keywords:
Acute intestinal failureChronic intestinal failureHome parenteral nutritionIntestinal failureShort bowel syndromeShort gut syndrome

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Area of Science:

  • Gastroenterology
  • Clinical Nutrition
  • Digestive Health

Background:

  • Intestinal failure (IF) occurs when the gastrointestinal tract cannot meet nutritional needs.
  • It is a known complication of short bowel syndrome, malabsorption, and functional dysmotility.
  • Causes include Crohn's disease, vascular issues, radiation enteritis, obstruction, and congenital defects.

Purpose of the Study:

  • To review historical and current definitions of intestinal failure (IF).
  • To highlight the importance of a standardized IF classification for clinical guidelines.
  • To address challenges in IF recognition and management due to varied definitions.

Main Methods:

  • Literature review of IF definitions.
  • Analysis of historical and contemporary IF classification systems.
  • Examination of the impact of definitions on clinical practice.

Main Results:

  • Historically, IF lacked a uniform definition, complicating diagnosis and treatment.
  • Newer definitions and classifications offer a standardized approach to IF.
  • Standardization is vital for developing consistent IF clinical guidelines.

Conclusions:

  • A clear and consistent definition of intestinal failure is essential.
  • Standardized classification improves patient recognition and management.
  • This review emphasizes the critical role of updated IF definitions in clinical guidelines.