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A major antigen on the outer envelope of a human oral spirochete, Treponema denticola
T Umemoto1, I Namikawa, H Suido
1Department of Oral Microbiology, School of Dentistry, Asahi University, Gifu, Japan.
Infection and Immunity
|August 1, 1989
Abstract:
Human oral spirochetes are prominent inhabitants of subgingival plaque in patients with periodontal disease. By immunoelectron microscopy using protein A-gold complexes and either polyclonal mouse antiserum against the 53-kDa antigen or 53-kDa-antigen-specific monoclonal antibody, a major polypeptide antigen, with a molecular weight of 53,000 (molecular size, 53 kilodaltons [kDa]), of a human oral spirochete, Treponema denticola ATCC 33520, was found to localize on the surface of the outer envelope.