Related Experiment Videos
In vivo antigenic variation of Campylobacter flagellin
S M Logan1, P Guerry, D M Rollins
1Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada.
Infection and Immunity
|August 1, 1989
Abstract:
Campylobacter coli VC167 cells producing either antigenic phase 1 (P1) or phase 2 (P2) flagellins (as determined by characteristic protein and DNA patterns) were used to infect rabbits by the removable intestinal tie-adult rabbit diarrhea (RITARD) procedure. Rabbits infected with P2 cells shed predominantly P2 cells throughout the infection; in rabbits infected with P1 cells, a transition of fecal isolates from P1 to P2 was observed.