Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vagina01:26

Vagina

44.7K
The vaginal canal is a tubular structure averaging about 10 cm in length that acts as the entryway to the female reproductive system and the passageway for menstrual flow and childbirth. The interior walls of the vagina exhibit concentric folds called rugae and are topped by an area known as the fornix, which connects with the protruding cervical portion of the uterus. This canal is comprised of an external fibrous layer, a muscular middle layer, and an inner lining with mucosal rugae, which...
44.7K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1.3K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.3K
Surface Membrane Barriers01:18

Surface Membrane Barriers

3.3K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
3.3K
Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

1.9K
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
1.9K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

648
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
648
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

819
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
819

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vaccine Treatment and Evaluation Units: Why Support a "Ready Base" of Clinical Trial Sites?

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2025
Same author

Navigating the path forward for evidence-based management of long COVID.

Nature immunology·2025
Same author

DoxyPEP to Prevent Bacterial STIs-Ready for Prime Time?

JAMA internal medicine·2025
Same author

Vaginal Bacteria and Proinflammatory Host Immune Mediators as Biomarkers of Human Immunodeficiency Virus Acquisition Risk Among African Women.

The Journal of infectious diseases·2024
Same author

Uptake and Persistence of Safer Conception Strategies Among South African Women Planning for Pregnancy.

AIDS and behavior·2024
Same author

The Legacies of Walt Stamm.

Sexually transmitted diseases·2024

Related Experiment Video

Updated: Mar 17, 2026

Author Spotlight: Revolutionizing Research on Vaginal Microbiome Interactions Using a Vaginal Chip
08:15

Author Spotlight: Revolutionizing Research on Vaginal Microbiome Interactions Using a Vaginal Chip

Published on: February 16, 2024

3.6K

The Vaginal Microbiome: Current Understanding and Future Directions.

David H Martin1, Jeanne M Marrazzo2

  • 1Department of Epidemiology, Tulane University School of Public Health Departments of Medicine and Microbiology, Louisiana State University Health Sciences Center, New Orleans.

The Journal of Infectious Diseases
|July 25, 2016
PubMed
Summary

Experts identified key research priorities for bacterial vaginosis (BV), focusing on understanding its causes, improving treatments, and exploring the roles of sexual transmission and the genitourinary microbiome.

Keywords:
antibioticsbacterial vaginosisgenitourinary tractmicrobiomevaginalwomen's health

More Related Videos

Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization
12:37

Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization

Published on: April 14, 2016

40.5K
Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
08:53

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Published on: May 25, 2022

4.7K

Related Experiment Videos

Last Updated: Mar 17, 2026

Author Spotlight: Revolutionizing Research on Vaginal Microbiome Interactions Using a Vaginal Chip
08:15

Author Spotlight: Revolutionizing Research on Vaginal Microbiome Interactions Using a Vaginal Chip

Published on: February 16, 2024

3.6K
Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization
12:37

Efficient Nucleic Acid Extraction and 16S rRNA Gene Sequencing for Bacterial Community Characterization

Published on: April 14, 2016

40.5K
Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
08:53

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria

Published on: May 25, 2022

4.7K

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Genitourinary Health

Background:

  • Bacterial vaginosis (BV) is a common vaginal condition with complex epidemiology.
  • Existing knowledge gaps hinder effective treatment and prevention strategies for BV.

Purpose of the Study:

  • To summarize the outcomes of an expert technical consultation on bacterial vaginosis (BV).
  • To identify and prioritize critical research areas for advancing BV understanding and management.

Main Methods:

  • Expert technical consultation convened by the National Institute of Allergy and Infectious Diseases.
  • Discussion and consensus-building among leading researchers in the field of BV.

Main Results:

  • Consensus reached on key research priorities: BV pathogenesis, optimizing treatment, and epidemiological roles of sexual transmission versus endogenous infection.
  • Identified need for better characterization of vaginal microbiome subtypes.
  • Highlighted importance of applying advanced -omic technologies for pathogenesis research.

Conclusions:

  • Further investigation into the male and female genitourinary tract microbiomes is crucial.
  • Development of novel therapeutic agents for BV treatment is a significant priority.
  • Prioritizing research in BV pathogenesis, microbiome characterization, and treatment optimization is essential for clinical progress.