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Impaired urine concentrating ability in Itai-itai (ouch-ouch) disease
1Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
International Urology and Nephrology
|January 1, 1989
Abstract:
A case of Itai-itai (ouch-ouch) disease with reduced urinary kallikrein excretion and slightly enhanced renin-angiotensin-aldosterone system is described. Although it is well known that cadmium toxicity frequently affects the renal tubular lesions, this report is the first to demonstrate the impaired urine concentrating ability in this disease.