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Analytical capillary isotachophoresis after 50 years of development: Recent progress 2014-2016
Zdena Malá1, Petr Gebauer1, Petr Boček1
1Institute of Analytical Chemistry of the Czech Academy of Sciences, v.v.i, Brno, Czech Republic.
Electrophoresis
|July 25, 2016
Summary
This review surveys analytical Isotachophoresis (ITP) from 2014-2016, highlighting computer simulations for new phenomena and novel instrumentation. Modern ITP applications often integrate with other methods for enhanced separation.
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Isotachophoresis (ITP) is a key analytical separation technique.
- The review covers advancements in ITP from 2014 to early 2016.
- The 50th anniversary provides historical context for ITP development.
Purpose of the Study:
- To review recent advancements in analytical ITP.
- To discuss the current state-of-the-art in ITP theory, instrumentation, and applications.
- To highlight the historical development and future trends of ITP.
Main Methods:
- Literature review of analytical ITP papers published between 2014 and Q1 2016.
- Analysis of theoretical and experimental studies.
- Examination of instrumentation and application-focused research.
Main Results:
- Computer simulations remain crucial for discovering new phenomena in ITP theory.
- Instrumentation advancements include novel channel methodologies, porous media, and on-chip assays.
- ITP is increasingly used in pre-separation or preparative roles, often coupled with other techniques.
Conclusions:
- ITP continues to be a vital analytical technique with ongoing theoretical and instrumental development.
- The integration of ITP with other methods is a significant trend in modern analytical applications.
- Future research directions are suggested by the analysis of recent publications.

