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Published on: May 26, 2023
Endolymphatic Sac Tumor Showing Increased Activity on 68Ga DOTATATE PET/CT
Georgios Z Papadakis1, Corina Millo, Samira M Sadowski
1From the *Radiology and Imaging Sciences, Warren Grant Magnuson Clinical Center, †Division of Nuclear Medicine, RAD&IS, Clinical Center, and ‡Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD; §Endocrine and Thoracic Surgery, University Hospitals of Geneva, Geneva, Switzerland; and ∥Center for Research in Computer Vision, Electrical and Computer Science Department, University of Central Florida, Orlando, FL.
None:
Endolymphatic sac tumors (ELSTs) are rare tumors arising from the epithelium of the endolymphatic sac and duct that can be either sporadic or associated with von Hippel-Lindau (VHL) disease. We report a case of a VHL patient with histologically proven residual ELST who underwent Ga DOTATATE PET/CT showing increased activity (SUVmax, 6.29) by the ELST. The presented case of a VHL-associated ELST with increased Ga DOTATATE uptake indicates cell-surface expression of somatostatin receptors by this tumor, suggesting the potential application of somatostatin receptor imaging using Ga DOTA-conjugated peptides in the workup and management of these patients.
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