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Updated: Mar 17, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Improving biomedical information retrieval by linear combinations of different query expansion techniques
Ahmed AbdoAziz Ahmed Abdulla1, Hongfei Lin2, Bo Xu1
1School of Computer Science and Technology, Dalian University of Technology, No.2 Linggong Rd., Dalian, 116024, People's Republic of China.
This study introduces a new method combining query expansion techniques to improve biomedical literature retrieval. The enhanced system significantly boosts search result accuracy, delivering more relevant documents to users.
Area of Science:
- Computer Science
- Information Science
- Biomedical Informatics
Background:
- Biomedical literature retrieval faces challenges due to increasing data complexity.
- Current information retrieval (IR) systems often yield low-quality results, failing to precisely meet user information needs.
- Users struggle to construct accurate queries for retrieving specific data from large document repositories.
Purpose of the Study:
- To enhance the performance of information retrieval systems in the biomedical domain.
- To refine IR searches by better representing user information needs through query expansion.
- To introduce a novel technique combining multiple query expansion methods.
Main Methods:
- Developed a system employing various query expansion techniques.
- Applied linear combinations to pairs of query expansion results.
- Tested the system's effectiveness in refining information retrieval searches.
Main Results:
- The combined query expansion approach significantly improved retrieval performance.
- The proposed system outperformed the baseline by 21.06% in retrieval accuracy (MAP).
- The method also showed improvement over a previous study, outperforming it by 7.12%.
Conclusions:
- Proposed and validated a novel approach using linear combinations of query expansion techniques.
- The method enhances the cognizability of user queries for search engines.
- Achieved higher-quality search results, addressing limitations of basic IR systems.
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