Neuropsychiatric manifestations of Parkinson's disease
Rosa M Molina Ruiz1, Andrew H Evans2, Dennis Velakoulis3
1Hospital Universitario Fundación Alcorcón, Universidad Rey Juan Carlos, Madrid, Spain rmolinar@salud.madrid.org.
Objective:
This clinical update review focuses on the classification and description of common neuropsychiatric manifestations in Parkinson's disease (PD).
Method:
We conducted a systematic search of the literature using Pubmed and selected the most recent and relevant papers for this review.
Results:
Neuropsychiatric manifestations in PD are are very frequent and may arise from an abnormal psychopathological response to the disease, neurobiological changes related to the disease itself, complications of treatments or a combination of all of these.
Conclusions:
Neuropsychiatric symptoms may precede the motor clinical presentation of PD. Early recognition is essential.
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