Related Experiment Video
Updated: Mar 17, 2026
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
[Patterns of ocular neurovascular reactions]
V I Lazarenko1, A S Kadantseva2, Yu I Savchenkov1
1Krasnoyarsk State Medical University named after prof. V.F. Voyno-Yasenetsky, 1 Partizana Zeleznyaka St., Krasnoyarsk, Russian Federation, 660022.
Aim:
To examine factors and determinants of ocular neurovascular reactions (NVR).
Material And Methods:
The study included 120 healthy participants of both sexes aged 20.9±0.6 years, who underwent a standard ophthalmic examination. Ocular microcirculation was recorded using laser Doppler flowmetry. Autonomic homeostasis and the intensity of slow-wave oscillations of hemodynamics were of interest. Autoregulation of cerebral blood flow was assessed by transcranial color-coded duplex scanning.
Results:
The dynamics of perfusion control mechanisms (myogenic and neurogenic) have been studied in the young healthy population of Krasnoyarsk. The role of the autonomic nervous system in initiating a particular type of ocular NVR has been identified. The authors have also determined the significance of the nitric oxide production intensity in different types of NVR.
Conclusion:
The type of ocular NVR is determined by parameters of cerebral hemodynamics. Normotonic NVR is associated with effective autoregulation of cerebral blood flow, while hyper- and hypotonic types of reactions - with autoregulatory failure.
