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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

8.4K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
8.4K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.7K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.4K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Disorders of Leukocytes01:27

Disorders of Leukocytes

2.3K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
2.3K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

10.1K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
10.1K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

16.5K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
16.5K

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Related Experiment Video

Updated: Mar 17, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Spontaneous Murine Model of Anaplastic Thyroid Cancer

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Malignant Lymphoma of the Thyroid.

K Aozasa1, M Ohsawa1

  • 1a Department of Pathology, Nara Medical University, Japan.

Leukemia & Lymphoma
|July 27, 2016
PubMed
Summary

Thyroid lymphoma, often linked to chronic lymphocytic thyroiditis (CLTH), presents diagnostic challenges. Advances in immunology and molecular biology aid in its diagnosis and understanding.

Area of Science:

  • Immunology
  • Oncology
  • Pathology

Background:

  • Thyroid lymphoma is a rare malignancy with a suspected association with chronic lymphocytic thyroiditis (CLTH).
  • Histological differentiation of thyroid lymphoma from small cell carcinoma and CLTH has historically been difficult.
  • Recent advancements in immunological methods and molecular biology have improved diagnostic capabilities.

Purpose of the Study:

  • To review recent studies on thyroid lymphoma, focusing on its relationship with CLTH.
  • To discuss the etiology, classification, cellular characteristics, prognosis, and diagnostic approaches for thyroid lymphoma.

Main Methods:

  • Review of pertinent literature on thyroid lymphoma.
  • Analysis of recent study results concerning thyroid lymphoma.
Keywords:
EB virusMalignant lymphomaepidemiologyimmunologypathologythyroid gland

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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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Related Experiment Videos

Last Updated: Mar 17, 2026

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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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  • Comparison of immunologic conditions in thyroid lymphoma versus CLTH.

    • Main Results:

    • Chronic lymphocytic thyroiditis (CLTH) plays a significant role in the etiology of thyroid lymphoma.
    • Intermediate lymphocytic lymphoma is relatively common; proliferating cells are of B-cell origin.
    • Aspiration cytology is valuable for early detection of thyroid lymphoma.

    Conclusions:

    • Immunological advancements have provided a scientific basis for diagnosing thyroid lymphoma.
    • Histological classification and clinical factors influence prognosis.
    • Early detection through aspiration cytology is crucial for managing thyroid lymphoma.