Related Experiment Videos
The hypo-osmotic swelling test and the sperm mucus penetration test in determining fertilization of the human oocyte
C L Barratt1, J C Osborn, P E Harrison
1Harris Birthright Centre for Reproductive Medicine, Department of Obstetrics and Gynaecology, University of Sheffield, Jessop Hospital for Women, UK.
Human Reproduction (Oxford, England)
|May 1, 1989
Abstract:
The usefulness of the hypo-osmotic swelling (HOS) test and the sperm mucus penetration (SMP) test as sperm function tests for in-vitro fertilization was analysed in 56 couples. Using logistic regression analysis only the SMP test was independently related to fertilization (P = 0.004), no false negative results were obtained, i.e. no fertilization if sperm from the ejaculate failed to penetrate mucus. The HOS test was of no predictive value. The results justify a further examination of the SMP test in other IVF centres.