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Updated: Mar 17, 2026

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
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The use of Immunoglobulin Therapy in Primary Immunodeficiency Diseases

Gholamreza Azizi, Hassan Abolhassani, Mohammad Hosein Asgardoon

  • 1Children's Medical Center Hospital, 62 Qarib St. Keshavarz Blvd. Tehran 14194, Iran

Endocrine, Metabolic & Immune Disorders Drug Targets
|July 27, 2016
PubMed

Immunoglobulin therapy represents a lifesaving intervention for many patients with primary immunodeficiency (PID). Antibody defects represent approximately half of the well-known PIDs requiring immunoglobulin replacement therapy. Following immunoglobulin therapy in PID patients, protection against serious upper and lower respiratory tract infections and pulmonary function improves which leads to an increase in the quality of life of these patients. Successful treatment of PID patients depends on the type of immunodeficiency, regular monitoring of the patient, comorbidities of the patient, and the availability of the products.

Keywords:
Immunoglobulininfectionprimary antibody deficiencyprimary immunodeficiency diseases

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