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Relapse of Hodgkin's Disease After 14 Years of Complete Remission
L C Platanias1, R A Larson1, J Anastasi1
1a Departments of Medicine and Pathology, The University of Chicago, Section of Hematology/Oncology, Chicago, IL 60637, USA.
Abstract:
A 40 year old male patient with nodular lymphocyte predominance Hodgkin's disease had a nodal relapse of the mixed cellularity subtype 14 years after entering complete remission with total nodal irradiation. This case is unusual because of the very long disease-free interval and also because the histology at relapse changed to the mixed cellularity subtype. A review of the literature of late relapses in Hodgkin's disease is presented, and possible mechanisms involved in their development are discussed. Hodgkin's disease.
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