Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Osmoregulation in Fishes02:32

Osmoregulation in Fishes

52.6K
When cells are placed in a hypotonic (low-salt) fluid, they can swell and burst. Meanwhile, cells in a hypertonic solution—with a higher salt concentration—can shrivel and die. How do fish cells avoid these gruesome fates in hypotonic freshwater or hypertonic seawater environments?
52.6K
Responses to Salt Stress02:02

Responses to Salt Stress

14.2K
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
14.2K
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

65.2K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
65.2K
Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

4.4K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
4.4K
Stress Response System01:21

Stress Response System

591
The stress response system, also known as the fight-or-flight response, is the body's automatic physiological reaction to perceived threats. Hans Selye introduced the concept of General Adaptation Syndrome (GAS) to describe the predictable pattern of changes that occur in response to stress. GAS consists of three sequential stages: alarm, resistance, and exhaustion. This model helps explain how chronic stress can contribute to health problems.
Alarm stage
In the alarm stage, the body's...
591
Hormonal Regulation of Blood Pressure01:17

Hormonal Regulation of Blood Pressure

5.7K
Endocrinal or hormonal intervention in the cardiovascular system is predominantly exerted by the catecholamines - epinephrine and norepinephrine, as well as a slew of hormones that interact with renal function to modulate blood volume.
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction...
5.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ontogeny of cortisol reaction norms in wild bonobos (Pan paniscus).

Proceedings. Biological sciences·2026
Same author

Dominant baboons experience more interrupted and less rest at night.

Current biology : CB·2025
Same author

Assessing Gestation and Fetal Sex in Wild Assamese Macaques Using Urinary Estrogen Analysis.

American journal of primatology·2025
Same author

The coevolution of cognition and sociality.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2025
Same author

Prenatal sex determination illuminates the unusual adult sex ratio of a group-living lemur.

Biology letters·2025
Same author

Early prenatal but not postnatal glucocorticoid exposure is associated with enhanced HPA axis activity into adulthood in a wild primate.

Proceedings. Biological sciences·2025

Related Experiment Video

Updated: Jan 5, 2026

Cortisol Extraction from Sturgeon Fin and Jawbone Matrices
06:01

Cortisol Extraction from Sturgeon Fin and Jawbone Matrices

Published on: September 10, 2019

8.6K

Cortisol coregulation in fish.

Ines Fürtbauer1, Michael Heistermann2

  • 1Department of Biosciences, College of Science, Swansea University, SA2 8PP Swansea, UK.

Scientific Reports
|July 27, 2016
PubMed
Summary
This summary is machine-generated.

Cortisol coregulation, the synchronization of physiological stress responses between partners, was observed in three-spined stickleback fish. This stress response covariation occurred in challenging environments, suggesting an ancient vertebrate adaptation.

More Related Videos

Behavioral Approaches to Studying Innate Stress in Zebrafish
05:29

Behavioral Approaches to Studying Innate Stress in Zebrafish

Published on: May 1, 2019

9.6K
A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System
13:22

A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System

Published on: September 10, 2013

12.4K

Related Experiment Videos

Last Updated: Jan 5, 2026

Cortisol Extraction from Sturgeon Fin and Jawbone Matrices
06:01

Cortisol Extraction from Sturgeon Fin and Jawbone Matrices

Published on: September 10, 2019

8.6K
Behavioral Approaches to Studying Innate Stress in Zebrafish
05:29

Behavioral Approaches to Studying Innate Stress in Zebrafish

Published on: May 1, 2019

9.6K
A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System
13:22

A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System

Published on: September 10, 2013

12.4K

Area of Science:

  • Comparative physiology
  • Neuroendocrinology
  • Ethology

Background:

  • Cortisol coregulation, the alignment of physiological stress responses between partners, is documented in species with strong social bonds.
  • Its presence in species lacking such bonds, and its evolutionary origins, remain largely unexplored.

Purpose of the Study:

  • To investigate cortisol coregulation in three-spined stickleback fish (Gasterosteus aculeatus) dyads.
  • To determine if cortisol levels covary between fish in shared environments, particularly under stress.
  • To explore the potential evolutionary basis of cortisol coregulation in vertebrates.

Main Methods:

  • Utilized a repeated measures design with non-invasive waterborne analysis of cortisol levels.
  • Compared cortisol levels in stickleback dyads in a familiar home tank versus a more stressful open field environment.
  • Employed time-lag analysis to assess the directionality of cortisol covariation.

Main Results:

  • Dyadic cortisol levels were not correlated in the home tank environment.
  • Significant cortisol covariation was observed between fish sharing the more stressful open field environment.
  • Time-lag analysis indicated that one fish's cortisol level predicted its partner's level during the shared stressful experience.

Conclusions:

  • Provides the first evidence of cortisol coregulation in a non-human species lacking strong social attachment.
  • Suggests that cortisol coregulation may be a conserved vertebrate trait with ancient evolutionary origins.
  • Proposes that cortisol coregulation may be an adaptive mechanism for mitigating risk in challenging situations.