Modification of Shape Memory Polymer Foams Using Tungsten, Aluminum Oxide, and Silicon Dioxide Nanoparticles

Area of Science:

• Biomaterials Science
• Polymer Chemistry
• Medical Device Engineering

Background:

• Shape memory polymer (SMP) foams are used for cerebral aneurysm embolization.
• Existing SMP foams have limitations due to potential strut fracture and particulate generation.

Purpose of the Study:

• To improve the mechanical properties and safety of SMP foams for aneurysm embolization.
• To investigate the effects of incorporating tungsten, silicon dioxide, and aluminum oxide nanoparticles into SMP foams.

Main Methods:

• Synthesis of SMP foams with three different nanoparticles.
• Thermal and mechanical characterization of the resulting nanocomposites.
• Evaluation of actuation profiles, thermal stability, and particulate release.

Main Results:

• Improved mechanical strength and toughness in SMP nanocomposites with low filler content.
• Faster SMP foam actuation with higher filler content.
• Enhanced thermal stability and minimal particulate generation below safety limits.

Conclusions:

• SMP nanocomposites exhibit tailorable mechanical properties, thermal resistivity, and actuation profiles.
• These materials show potential for use in medical devices, particularly for aneurysm embolization.
• Further investigation into nanoparticle release, especially tungsten, is warranted.